Wonbeak Yoo

About

Dr. Yoo is a researcher at Korea Research Institute of Bioscience and Biotechnology (KRIBB). Dr. Yoo received a Ph.D. degree in 2013 (College of Medicine, Korea University). He worked as a postdoctoral fellow at the department of molecular and cellular oncology (MD Anderson Cancer Center at Houston, USA). After a postdoctoral course, he worked as a researcher at KAIST, KRIBB, and AceBiome Inc. (Daejeon, South Korea). Dr. Yoo's research interests include (1) causes, mechanisms, and experimental therapy for cancers; (2) cancer related disease including anorexia-cachexia; (3) development of diagnostic and prognostic markers for cancer; (4) metabolic dysfunction-associated steatotic liver disease (MASLD); (5) microbiome and application for human health; (6) establishment and utilization of preclinical experimental in vitro and in vivo models; (7) bioinformatic validation for biomarkers. Overall, his interests are on the translational cancer research, bridging the basic research with novel therapeutic approaches development.

Work

Korea Research Institute of Bioscience and Biotechnology

Korea (Republic of)

Education

Korea University

Korea (Republic of)
Ph.D.

Publications

Therapeutic potential of anti-ErbB3 chimeric antigen receptor natural killer cells against breast cancer

Cancer Immunology, Immunotherapy

journal-article

Targeting CD155 in lung adenocarcinoma: A5 nanobody-based therapeutics for precision treatment and enhanced drug delivery

Signal Transduction and Targeted Therapy

journal-article

Therapeutic potential of anti-ErbB3 chimeric antigen receptor natural killer cells against breast cancer

Cancer Immunology Immunotherapy

journal-article

Targeting CD155 in lung adenocarcinoma: A5 nanobody-based therapeutics for precision treatment and enhanced drug delivery

Signal Transduction and Targeted Therapy

journal-article

Role of SYT11 in human pan-cancer using comprehensive approaches

European Journal of Medical Research

journal-article

Comprehensive analysis on clinical significance and therapeutic targets of LDL receptor related protein 11 (LRP11) in liver hepatocellular carcinoma

Frontiers in Pharmacology

journal-article

Loliolide in Sargassum horneri Alleviates Ultrafine Urban Particulate Matter (PM 0.1)-Induced Inflammation in Human RPE Cells

International Journal of Molecular Sciences

journal-article

Comprehensive analysis on clinical significance and therapeutic targets of LDL receptor related protein 11 (LRP11) in liver hepatocellular carcinoma

Frontiers in Pharmacology

journal-article

CRHBP, a novel multiple cancer biomarker connected with better prognosis and anti-tumorigenicity

Cancer Cell International

journal-article

CRHBP, a novel multiple cancer biomarker connected with better prognosis and anti-tumorigenicity

Cancer Cell International

journal-article

Role of SYT11 in human pan-cancer using comprehensive approaches

Research Square

other

Comprehensive analysis on clinical significance and therapeutic targets of LDL receptor related protein 11 (LRP11) in liver hepatocellular carcinoma

Frontiers in Pharmacology

journal-article

Loliolide in Sargassum horneri Alleviates Ultrafine Urban Particulate Matter (PM 0.1)-Induced Inflammation in Human RPE Cells

International Journal of Molecular Sciences

journal-article

Role of SYT11 in human pan-cancer using comprehensive approaches

European Journal of Medical Research

journal-article

Role of SYT11 in human pan-cancer using comprehensive approaches

European Journal of Medical Research

journal-article

SAMD13 serves as a useful prognostic biomarker for hepatocellular carcinoma

European Journal of Medical Research

journal-article

Loliolide in Sargassum horneri Alleviates Ultrafine Urban Particulate Matter (PM 0.1)-Induced Inflammation in Human RPE Cells

International Journal of Molecular Sciences

journal-article

SAMD13 serves as a useful prognostic biomarker for hepatocellular carcinoma

European Journal of Medical Research

journal-article

SAMD13 serves as a useful prognostic biomarker for hepatocellular carcinoma

European Journal of Medical Research

journal-article

Overcoming adaptive resistance to anti-VEGF therapy by targeting CD5L

Nature Communications

journal-article

Overcoming adaptive resistance to anti-VEGF therapy by targeting CD5L

Nature Communications

journal-article

Overcoming adaptive resistance to anti-VEGF therapy by targeting CD5L

Nature Communications

journal-article

Inhibitory effect of fucoidan on TNF-α-induced inflammation in human retinal pigment epithelium cells

Frontiers in Nutrition

journal-article

Inhibitory effect of fucoidan on TNF-α-induced inflammation in human retinal pigment epithelium cells

Frontiers in Nutrition

journal-article

Inhibitory effect of fucoidan on TNF-α-induced inflammation in human retinal pigment epithelium cells

Frontiers in Nutrition

journal-article

Anti-Itching and Anti-Inflammatory Effects of Kushenol F via the Inhibition of TSLP Production

Pharmaceuticals

journal-article

Anti-Melanogenic and Antioxidant Effects of Cell-Free Supernatant from Lactobacillus gasseri BNR17

Microorganisms

journal-article

Anti-Itching and Anti-Inflammatory Effects of Kushenol F via the Inhibition of TSLP Production

Pharmaceuticals

journal-article

Anti-Melanogenic and Antioxidant Effects of Cell-Free Supernatant from Lactobacillus gasseri BNR17

Microorganisms

journal-article

Anti-Melanogenic and Antioxidant Effects of Cell-Free Supernatant from Lactobacillus gasseri BNR17

Microorganisms

journal-article

Nanodiamond as a Cytokine Sponge in Infectious Diseases

Frontiers in Bioengineering and Biotechnology

journal-article

Nanodiamond as a Cytokine Sponge in Infectious Diseases

Frontiers in Bioengineering and Biotechnology

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Nanodiamond as a Cytokine Sponge in Infectious Diseases

Frontiers in Bioengineering and Biotechnology

journal-article

Anti-Itching and Anti-Inflammatory Effects of Kushenol F via the Inhibition of TSLP Production

Pharmaceuticals

journal-article

Anti-Itching and Anti-Inflammatory Effects of Kushenol F via the Inhibition of TSLP Production

Pharmaceuticals

journal-article

Pancreatic cancer induces muscle wasting by promoting the release of pancreatic adenocarcinoma upregulated factor

Experimental & Molecular Medicine

journal-article

The Effect of Lactobacillus gasseri BNR17 on Postmenopausal Symptoms in Ovariectomized Rats

Journal of Microbiology and Biotechnology

journal-article

The Effect of Lactobacillus gasseri BNR17 on Postmenopausal Symptoms in Ovariectomized Rats

Journal of Microbiology and Biotechnology

journal-article

The effect of lactobacillus gasseri bnr17 on postmenopausal symptoms in ovariectomized rats

Journal of Microbiology and Biotechnology

journal-article

Tumour-derived Dilp8/INSL3 induces cancer anorexia by regulating feeding neuropeptides via Lgr3/8 in the brain

Nature Cell Biology

journal-article

Tumour-derived Dilp8/INSL3 induces cancer anorexia by regulating feeding neuropeptides via Lgr3/8 in the brain

Nature Cell Biology

journal-article

Tumour-derived Dilp8/INSL3 induces cancer anorexia by regulating feeding neuropeptides via Lgr3/8 in the brain

Nature Cell Biology

journal-article

Pancreatic cancer induces muscle wasting by promoting the release of pancreatic adenocarcinoma upregulated factor

Experimental and Molecular Medicine

journal-article

Pancreatic cancer induces muscle wasting by promoting the release of pancreatic adenocarcinoma upregulated factor

Experimental and Molecular Medicine

journal-article

Diversity in the Extracellular Vesicle-Derived Microbiome of Tissues According to Tumor Progression in Pancreatic Cancer

Cancers

journal-article

Diversity in the extracellular vesicle-derived microbiome of tissues according to tumor progression in pancreatic cancer

Cancers

journal-article

Diversity in the Extracellular Vesicle-Derived Microbiome of Tissues According to Tumor Progression in Pancreatic Cancer

Cancers

journal-article

Diversity in the Extracellular Vesicle-Derived Microbiome of Tissues According to Tumor Progression in Pancreatic Cancer

Cancers

journal-article

Ubiquitination of PPAR-gamma by pVHL inhibits ACLY expression and lipid metabolism, is implicated in tumor progression

Metabolism

journal-article

Ubiquitination of PPAR-gamma by pVHL inhibits ACLY expression and lipid metabolism, is implicated in tumor progression

Metabolism Clinical and Experimental

journal-article

Ubiquitination of PPAR-gamma by pVHL inhibits ACLY expression and lipid metabolism, is implicated in tumor progression

Metabolism

journal-article

The YAP1–NMU Axis Is Associated with Pancreatic Cancer Progression and Poor Outcome: Identification of a Novel Diagnostic Biomarker and Therapeutic Target

Cancers

journal-article

Arazyme Suppresses Hepatic Steatosis and Steatohepatitis in Diet-Induced Non-Alcoholic Fatty Liver Disease-Like Mouse Model

International Journal of Molecular Sciences

journal-article

Arazyme suppresses hepatic steatosis and steatohepatitis in diet-induced non-alcoholic fatty liver disease-like mouse model

International Journal of Molecular Sciences

journal-article

Progranulin attenuates liver fibrosis by downregulating the inflammatory response

Cell Death & Disease

journal-article

Progranulin attenuates liver fibrosis by downregulating the inflammatory response

Cell Death and Disease

journal-article

Progranulin attenuates liver fibrosis by downregulating the inflammatory response

Cell Death and Disease

journal-article

The YAP1–NMU Axis Is Associated with Pancreatic Cancer Progression and Poor Outcome: Identification of a Novel Diagnostic Biomarker and Therapeutic Target

Cancers

journal-article

The YAP1-NMU Axis Is Associated with Pancreatic Cancer Progression and Poor Outcome: Identification of a Novel Diagnostic Biomarker and Therapeutic Target

Cancers

journal-article

The YAP1–NMU axis is associated with pancreatic cancer progression and poor outcome: Identification of a novel diagnostic biomarker and therapeutic target

Cancers

journal-article

Arazyme Suppresses Hepatic Steatosis and Steatohepatitis in Diet-Induced Non-Alcoholic Fatty Liver Disease-Like Mouse Model

International Journal of Molecular Sciences

journal-article

Arazyme Suppresses Hepatic Steatosis and Steatohepatitis in Diet-Induced Non-Alcoholic Fatty Liver Disease-Like Mouse Model

International Journal of Molecular Sciences

journal-article

An Antibody Designed to Improve Adoptive NK-Cell Therapy Inhibits Pancreatic Cancer Progression in a Murine Model

Cancer Immunology Research

journal-article

An antibody designed to improve adoptive NK-cell therapy inhibits pancreatic cancer progression in a murine model

Cancer Immunology Research

journal-article

An antibody designed to improve adoptive NK-cell therapy inhibits pancreatic cancer progression in a murine model

Cancer Immunology Research

journal-article

Fatty acids in non-alcoholic steatohepatitis: Focus on pentadecanoic acid

PLOS ONE

journal-article

Fatty acids in non-alcoholic steatohepatitis: Focus on pentadecanoic acid

Plos One

journal-article

Fatty acids in non-alcoholic steatohepatitis: Focus on pentadecanoic acid

Plos One

journal-article

Pro-inflammatory hepatic macrophages generate ROS through NADPH oxidase 2 via endocytosis of monomeric TLR4–MD2 complex

Nature Communications

journal-article

Pro-inflammatory hepatic macrophages generate ROS through NADPH oxidase 2 via endocytosis of monomeric TLR4-MD2 complex

Nature Communications

journal-article

Pro-inflammatory hepatic macrophages generate ROS through NADPH oxidase 2 via endocytosis of monomeric TLR4-MD2 complex

Nature Communications

journal-article

Multifunctional Effects of a Small-Molecule STAT3 Inhibitor on NASH and Hepatocellular Carcinoma in Mice

Clinical Cancer Research

journal-article

Multifunctional effects of a small-molecule STAT3 inhibitor on NASH and hepatocellular carcinoma in mice

Clinical Cancer Research

journal-article

Multifunctional Effects of a Small-Molecule STAT3 Inhibitor on NASH and Hepatocellular Carcinoma in Mice

Clinical Cancer Research

journal-article

Fusion protein of retinol‐binding protein and albumin domain III reduces liver fibrosis

EMBO Molecular Medicine

journal-article

Fusion protein of retinol-binding protein and albumin domain III reduces liver fibrosis

EMBO Molecular Medicine

journal-article

Non-invasive Diagnosis of Non-alcoholic Steatohepatitis (NASH) using a Panel of Fatty Acids

Hepatology

journal-article

HIF-1α Expression as a Protective Strategy of HepG2 Cells Against Fatty Acid-Induced Toxicity

Journal of Cellular Biochemistry

journal-article

Sleep fragmentation induces reduction of synapsin II in rat hippocampus

Sleep and Biological Rhythms

journal-article

HIF-1α Expression as a Protective Strategy of HepG2 Cells Against Fatty Acid-Induced Toxicity

Journal of Cellular Biochemistry

journal-article

An association study of polymorphisms in JAK3 gene with lung cancer in the Korean population

Cancer Research and Treatment

journal-article

An Association Study of Polymorphisms in JAK3 Gene with Lung Cancer in the Korean Population

Cancer Research and Treatment

journal-article

An Association Study of Polymorphisms in JAK3 Gene with Lung Cancer in the Korean Population

Cancer Research and Treatment

journal-article

Albumin expression is required for adipocyte differentiation of 3T3-L1 cells

Biochemical and Biophysical Research Communications

journal-article

Albumin expression is required for adipocyte differentiation of 3T3-L1 cells

Biochemical and Biophysical Research Communications

journal-article

Formation of vitamin A lipid droplets in pancreatic stellate cells requires albumin

Gut

journal-article